FLU-PROFEN 50 - 100 (FILM COATED TABLETS)

Non steroidal anti-inflammatory

 

COMPOSITION:
Each coated tablet contains 50 or 100 mg flurbiprofen.

MECHANISM OF ACTION:
Flurbiprofen is an inhibitor of prostaglandin synthetase.

INDICATIONS:
FLU-PROFEN is indicated for its analgesic and anti-inflammatory effects in the treatment of rheumatoid disease, ankylosing spondylitis, osteoarthritis. FLU-PROFEN is indicated in peri-articular conditions such as frozen shoulder (capsulitis), bursitis, tendinitis, tenosynovitis, and low back pain, and in other musculo-skeletal and joint disorders, such as sprains and strains. FLU-PROFEN is used for the relief of mild to moderate pain in conditions such as: dysmenorrhoea, dental and post-operative pain, migraine.

DOSAGE AND ADMINISTRATION:
150 – 200mg daily in divided doses. In severe or acute conditions the total daily dose not exceeds 300mg in divided doses. No special dosage modifications are required for elderly patients, unless renal or hepatic function is impaired, in which case dosage should be assessed individually. FLU-PROFEN is not indicated for use in children.

SIDE EFFECTS:
Gastrointestinal disturbances, peptic ulceration, gastrointestinal bleeding, headache, dizziness, nervousness, skin rash, pruritus, oedema, depression, drowsiness, insomnia, and blurred vision.
Hypersensitivity reactions, impairment of renal function including interstitial nephritis or the nephrotic syndrome. Agranulocytosis and thrombocytopenia have occasionally been observed.

CONTRAINDICATIONS:
Peptic ulceration, gastrointestinal hemorrhage, ulcerative colitis, patients in whom aspirin and other non steroidal anti-inflammatory drugs induce the symptoms of asthma, rhinitis or urticaria,

DRUG INTERACTIONS:
As with other non steroidal anti-inflammatory agents, caution should be exercised in patients receiving oral anticoagulants and thiazide diuretics.

PRECAUTIONS:

  1. Non steroidal anti-inflammatory drugs have been reported to cause nephrotoxicity in various forms.
  2. In patients with renal, cardiac or hepatic impairment, caution is required since the use of non steroidal anti-inflammatory drugs may result in deterioration of renal function. The dose should be kept as low as possible and renal function should be monitored.
  3. FLU-PROFEN should be used with caution in patients with a history of cardiac decompensation and hypertension.
  4. FLU-PROFEN may prolong bleeding time, it should be used with caution in patients with a potential for abnormal bleeding.

USE IN PREGNANCY AND LACTATION:
The safety of flurbiprofen during pregnancy or lactation has not been established.

PRESENTATION:
Carton pack contains 2 blisters of 20 film coated tablets of 50mg or blister of 10 film coated tablets of 100mg, with leaflet.

 

 

 
 
 

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