Lactolac   (SYRUP)

COMPOSITION:
Each 15ml of Lactolac Syrup contains 10g lactulose.

PROPERTIES:

The action of Lactolac in treating constipation depends on increased intra-colonic osmotic pressure (through resulting break down products of lactulose simple organic compounds like lactic and acetic acid), with consequent increased faecal bulk, and stimulation of peristalsis. A soft stool is formed, and normal bowel action encouraged without irritation or direct interference with the mucosa.

In patients with hepatic encephalopathy a significant reduction in the pH of the colonic contents, which reduces markedly the formation and absorption of ammonium ions and other nitrogenous break down into the portal circulation.

INDICATIONS:
Constipation, hepatic encephalopathy (Portal systemic encephalopathy, hepatic coma).

DOSAGE:

  1. CONSTIPATION: Lactolac may, if necessary be taken with water or fruit juice. The dose should be adjusted to the needs of the individual, but the following serves as a guide:

Infants under 1 year: 2.5ml twice daily.
Children 1 – 5 years: 5ml twice daily.
Children 5 – 10 years: 10ml twice daily.
Adults: 15ml twice daily.

  1. HEPATIC ENCEPHALOPATHY:

Initial doses 30–50ml 3 times daily. Subsequently adjust the dose to produce 2 – 3 soft stools each day.
Lactolac is almost completely unabsorbed from the gastrointestinal tract, and 15ml of Lactolac per day provides only (14k calorie). It is safety for diabetics.

CONTRAINDICATIONS:
Galactosaemia, gastrointestinal obstruction, and Lactulose intolerance.

SIDE EFFECTS:
Flatulence may occur, and symptom usually disappears under continued therapy. Excessive dosage can lead to diarrhea with potential complications such as loss of fluids, (hypokalemia and hypernatremia).

DRUG INTERACTIONS:
Non-absorbable antacids given concurrently with lactulose may inhibit the desired lactulose-induced drop in colonic pH.

ABSORPTION AND ELIMINATION:
Lactolac is almost completely unabsorbed from the gastrointestinal tract. Urinary excretion has been determined to be 3% or less.

USE IN PREGNANCY:
The use of Lactolac is acceptable, if used in the recommended dosage.

PRESENTATION:
Carton pack contains bottle of 100 or 200ml, with leaflet.

 

 

 
 
 

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