Lexo-Zepam   (Tablets)

COMPOSITION:
Each tablet contains 1.5, or 3mg bromazepam.

INDICATIONS:
Lexo-Zepam is indicated for the short term treatment of: Severe anxiety, anxiety in psychosomatic, organic and psychotic illness.

DOSAGE AND ADMINISTRATION:
The optimum dosage and frequency of administration of Lexo-Zepam should be based on the individual patient, the severity of symptoms.
Adults: 3 – 18mg daily in divided doses. In rare circumstances in hospitalized patients up to the maximum dosage of 60mg daily in divided doses, may be given.
Elderly: Elderly patients are more sensitive to the action of drug, doses should not exceed half those normally recommended. Those suffering from cerebral vascular changes are likely to respond to smaller doses.

SIDE EFFECTS:
Drowsiness, sedation and ataxia. Other adverse effects rare and include: Headache, vertigo, hypotension, gastrointestinal disturbance, skin rashes, visual disturbances, changes in libido, and urinary retention.

CONTRAINDICATIONS:
Patients with a previous history of sensitivity to benzodiazepines, or patients with acute pulmonary insufficiency.

DRUG INTERACTIONS:
The sedative effects may be intensified, if Lexo-Zepam is combined with centrally acting drugs such as tranquilizers, antidepressants, hypnotics and anaesthetics.
Side effects and toxicity may be more evident, when Lexo-Zepam is used in conjunction with antiepileptic drugs particularly with hydantoins or barbiturates.
Know inhibitors of hepatic enzymes such as cimetidine have been shown to reduce the clearance of benzodiazepines.

PRECAUTIONS:

  1. While taking the drug patient should be cautious while driving or operating machinery until it is established that they do not become dizzy or drowsy.
  2. The drug should be used with caution in patients with personality disorders.
  3. In patients with chronic pulmonary insufficiency, chronic renal or hepatic disease dosage may need to be reduced.
  4. The long and regular use of drug may cause addiction. 

USE IN PREGNANCY AND LACTATION:
Do not use during pregnancy especially during the first and last trimesters unless there are compelling reasons. Benzodiazepines have been detected in breast milk. If possible it should be avoided during lactation.

PRESENTATION:
Carton pack contains 2 blisters each of 10 tablets of 1.5 or 3mg, with leaflet.

 

 

 
 
 

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