COMPOSTION:

Each tablet contains 5mg Nitrazepam.

INDICATIONS:

Mogam has essential effects on CNS, and it is one of the 1,4 Benzodiazepines groups. It is similar to this group in its effects and has sedative properties.

Mogam is indicated for a short term treatment of severe insomnia.

DOSAGE:

• Children: Not recommended.
• Adults: 5mg before retiring, it may be increased to 10mg if necessary.
• Elderly: 2.5mg before retiring, it may be increased to 5mg if necessary.

CONTRAINDICATIONS:

Sensitivity to benzodiazepines, acute pulmonary insufficiency and chronic psychosis.

SIDE EFFECTS:

The common side effects: Drowsiness, sedation, blurring of vision and ataxia. Other side effects, which occur rarely such as: Headache, dizziness, gastrointestinal disturbances and skin rashes.

DRUG INTERACTIONS:

If Mogam is combined with centrally acting drugs such as: Neuroleptics, tranquilizers, antidepressants, hypnotics, analgesics, and anesthetics, the sedative effects are likely to be intensified. When Mogam is used in conjunction with antiepileptic drugs, side effects and toxicity may be more evident particularly with hydantoin or barbiturates. Inhibitors of hepatic enzymes, e.g. cimetidine, reduce the clearance of benzodiazepines and may potentiate their action. The inducers of hepatic enzymes, e.g. rifampicin, may increase the clearance of Mogam.

PRECAUTIONS:

• Patients should be warned of the possible hazard and advised not to drive or operate machinery.
• Patients should avoid drinking alcohol during treatment.
• Benzodiazepies should not be used alone to treat depression, as suicide may be precipitated in such patients.
• Treatment should not be continued for more than 4 weeks and therapy must be stopped gradually.
• In all cases Mogam is to be dispensed only under medical prescription.

USE IN PREGNANCY OR LACTATION:

For compelling medical reason it can be administered during the late phase of pregnancy. But nursing woman should not use it.