Compostion:
Each 1ml solution contains 20mg Sodium Cromoglicate.
Preservative: Benzalkonium chloride.
Pharmacodynamic Properties:
the solution exerts its effect locally in the eyes . sodium cromoglicate has been shown to inhibt the degranulation of sessitied mast cells occuring after exposure to specific antigens .Sodium cromoglicate inhibts releasw of histamine and various membrane-derived mediators from mast cells .Sodium cromoglicate has no intrinsic antihistaminic or vasoconstrictor activity.
Pharmacokenitic Properities :
limited systemic absorption may be expected via ocular instillation . approximately 0.03% of sodium cromoglicate is absorbed following ocular administration.
Indication:
indicated for the relief and treatment of seasonal and perennial allergic conjunctivitis.
Contraindication:
known hypersensitivity to sodium cromoglicate.
Special warning and precautions:
This solution is sterile , preservative free and presented in a single use container , which should be discarded after use.
Effects on ability to drive and use machines :
As with all eye drobs,transient blurring of vision may occur on instillation . do not drive or operate machinery until normal vision is restored.
Pregnancy & lactation :
Pregnancy :
it should be used with caution in pregnancy , especially during the first trimester . It should only be used in pregnancy where there is a clinical need
lactation:
It is not known whether sodium cromoglicateis excreted in breast milk ; however , on the basic of its physic chemical properties , it is considered unlikley.
Side effects:
on instillation , transient stinging or buring may occur .Rarely , other symptoms of local irritation have been reported .
Dosage and administration :
For topical opthalmic use .
Adults, children and the elderly : one or two drop into each eye 4 times per day or as directed by the doctor.
overdosage:
if the solution is accidentally ingested , as sodium cromoglicate is only poorly absorbed , no action other than medical supervision should be necessary .