Each tablet contains 1.5 or 3mg bromazepam.
Lexo-Zepam is indicated for the short term treatment of: Severe anxiety, anxiety in psychosomatic, organic and psychotic illness.
DOSAGE AND ADMINISTRATION:
The optimum dosage and frequency of administration of Lexo-Zepam should be based on the individual patient, the severity of symptoms.
Adults: 3 – 18mg daily in divided doses. In rare circumstances in hospitalized patients up to the maximum dosage of 60mg daily in divided doses, may be given.
Elderly: Elderly patients are more sensitive to the action of drug, doses should not exceed half those normally recommended. Those suffering from cerebral vascular changes are likely to respond to smaller doses.
Drowsiness, sedation and ataxia. Other adverse effects are rare and include: Headache, vertigo, hypotension, gastrointestinal disturbances, skin rashes, visual disturbances, changes in libido and urinary retention.
Patients with a previous history of sensitivity to benzodiazepines, or patients with acute pulmonary insufficiency.
The sedative effects may be intensified if Lexo-Zepam is combined with centrally acting drugs such as tranquilizers, antidepressants, hypnotics and anaesthetics.
Side effects and toxicity may be more evident when Lexo-Zepam is used in conjunction with antiepileptic drugs particularly with hydantoins or barbiturates.
Know inhibitors of hepatic enzymes such as cimetidine have been shown to reduce the clearance of benzodiazepines.
USE IN PREGNANCY AND LACTATION:
Do not use during pregnancy especially during the first and last trimesters unless there are compelling reasons. Benzodiazepines have been detected in breast milk. If possible it should be avoided during lactation.