Composition:

Each 100g Cream contains 5g acyclovir.

Mechanism of Action:

Virax is an antiviral agent which is highly active against herpes simplex virus (HSV) and varicella zoster. Virax is rapidly absorbed through corneal epithelium and superficial skin layers. Acyclovir is phosphorylated in the presence of thymidin kinase to mono, di- and tri-phosphate acyclovir. Acyclovir triphosphate acts as an inhibitor of the virus specified DNA polymerase, preventing further viral DNA Synthesis. Virax dose not phosphorylated in normal cells, therefore it affects specifically infected cells.

Indications:

Virax is indicated for the treatment of virus infections which cause herpes simplex of the skin including initial and recurrent genital herpes and herpes labialis, and for the treatment of varicella zoster.

Usage:

Apply Virax 5 times daily at approximately 4 hours interval. Treatment should be for 3 days after recovery. Therapy should begin as early as possible after the start of an infection. For recurrent episodes, therapy should begin when the lesion first appear.

Contraindications:

Hypersensitivity to acyclovir.

Side Effects:

Transient burning or stinging following application of Virax may occur. Erythema, itching, mild drying of the skin have been reported in a small proportion of patients.

Precaution:

The product is not recommended for application to eyes.

Use in Pregnancy or Lactation:

Experience in humans is limited, therefore the drug should not be used unless the potential benefits are more than the possibility of unexpected risks.