Each 100g Cream contains 1g Silver Sulphadiazine USP.
Floumizin has a broad antimicrobial activity against gram-positive and gram-negative bacteria, including pseudomonas aeruginosa, and some races of yeasts and fungi.
Floumizin is prescribed for:
When Floumizin is prescribed, it is recommended to use a new tube, as the cream should be sterile.
Local reactions may occur such as: Burning, itching, and skin rash. Leucopenia has been reported in 3-5% of burn patients, 2-3 days after treatment has been commenced. It is usually self limiting and therapy with Floumizin does not usually need to be stopped.
Hypersensitivity to Silver Sulphadiazine, premature infants, or infants during the first months of birth.
As Silver may inactivate pus enzymolytic agents, therefore its concomitant use with such enzymes may be inappropriate.
In large area burns, where serum Sulphadiazine levels may approach therapeutic levels, this affects other drugs such as oral hypoglycemic agents and phenytoin. In this case the dose of these drugs should be monitored as their effects can be potentiated.
Floumizin should be used with caution in these cases: Presence of significant hepatic, renal impairment, patients known to be sensitive to sulfonamides, and patients known to have glucose-6-phosphate dehydrogenase deficiency. Use of the drug may delay separation of burn eschar and may alter appearance of the burn wounds.
USE IN PREGNANCY:
The drug should not be used in pregnancy.