Each 15ml of Lactolac Syrup contains 10g lactulose.
The action of Lactolac in treating constipation depends on increased intra-colonic osmotic pressure (through resulting break down products of lactoluse simple organic compounds like lactic and acetic acid), with consequent increased faecal bulk, and stimulation of peristalsis. A soft stool is formed, and normal bowel action encouraged without irritation or direct interference with the mucosa.
In patients with hepatic encephalopathy a significant reduction in the pH of the colonic contents, which reduces markedly the formation and absorption of ammonium ions and other nitrogenous break down into the portal circulation.
Constipation, hepatic encephalopathy(Portal systemic encephalopathy, hepatic coma).
- CONSTIPATION: Lactolac may, if necessary be taken with water or fruit juice. The dose should be adjusted to the needs of the individual, but the following serves as a guide:
Infants under 1 year: 2.5ml twice daily.
Children 1 – 5 years: 5ml twice daily.
Children 5 – 10 years: 10ml twice daily.
Adults: 15ml twice daily.
- HEPATIC ENCEPHALOPATHY:
Initial doses 30–50ml 3 times daily. Subsequently adjust the dose to produce 2 – 3 soft stools each day.
Lactolac is almost completely unabsorbed from the gastro - intestinal tract, and 15ml of Lactolac per day provides only (14k calorie). It is safety for diabetics.
Galactosaemia, gastro-intestinal obstruction, and Lactulose intolerance.
Flatulence may occur, and symptom usually disappears under continued therapy. Excessive dosage can lead to diarrhea with potential complications such as loss of fluids, (hypokalemia and hypernatremia).
Non-absorbable antacid given concurrently with lactulose may inhibit the desired lactulose-induced drop in colonic PH.
ABSORPTION AND ELIMINATION:
Lactolac is almost completely unabsorbed from the gastrointentional tract. Urinary excretion has been determined to be 3% or less.
USE IN PREGNANCY:
The use of Lactolac is acceptable, if used in the recommended dosage.