Lactolac

Lactolac

COMPOSITION:

Each 15ml of Lactolac Syrup contains 10g lactulose.

PROPERTIES:

The action of Lactolac in treating constipation depends on increased intra-colonic osmotic pressure (through resulting break down products of lactoluse simple organic compounds like lactic and acetic acid), with consequent increased faecal bulk, and stimulation of peristalsis. A soft stool is formed, and normal bowel action encouraged without irritation or direct interference with the mucosa.

In patients with hepatic encephalopathy a significant reduction in the pH of the colonic contents, which reduces markedly the formation and absorption of ammonium ions and other nitrogenous break down into the portal circulation.

INDICATIONS:

Constipation, hepatic encephalopathy(Portal systemic encephalopathy, hepatic coma).

DOSAGE:

   - CONSTIPATION: Lactolac may, if necessary be taken with water or fruit juice. The dose should be adjusted to the needs of the individual, but the following         serves as a guide:

Infants under 1 year: 2.5ml twice daily.

Children 1 – 5 years: 5ml twice daily.

Children 5 – 10 years: 10ml twice daily.

Adults: 15ml twice daily.

   - HEPATIC ENCEPHALOPATHY:

Initial doses 30–50ml 3 times daily. Subsequently adjust the dose to produce 2 – 3 soft stools each day.

Lactolac is almost completely unabsorbed from the gastro - intestinal tract, and 15ml of Lactolac per day provides only (14k calorie). It is safety for diabetics.

CONTRAINDICATIONS:

Galactosaemia, gastro-intestinal obstruction, and Lactulose intolerance.

SIDE EFFECTS:

Flatulence may occur, and symptom usually disappears under continued therapy. Excessive dosage can lead to diarrhea with potential complications such as loss of fluids, (hypokalemia and hypernatremia).

DRUG INTERACTIONS:

Non-absorbable antacid given concurrently with lactulose may inhibit the desired lactulose-induced  drop in colonic PH.

ABSORPTION AND ELIMINATION:

Lactolac is almost completely unabsorbed from the gastrointentional tract. Urinary excretion has been determined to be 3% or less.

USE IN PREGNANCY:

The use of Lactolac is acceptable, if used in the recommended dosage.

Address

Domina Pharmaceuticals
P.O. Box : 9622
Damascus - Syria

Contacts

Email: info@dominapharm.com
Phone: +963 (11) 33 192 32
Phone: +963 (11) 33 201 04
Mobile: +963 (932) 993 304 159
Mobile: +963 (932) 993 366 254